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The Pastore Podcast

The Pastore Podcast

Join Dr. Robert Pastore and his co-host Lexie (@lexircise) as they discuss and clarify nutritional and neurochemical science. Dr. Pastore is also joined by guests from backgrounds of all types – from all-star athletes, to top trainers and coaches, to scientists and researchers - and dives deeply into the science behind optimizing performance and longevity.

Dr. Pastore is a Certified Nutrition Specialist, and holds an MS in Human Nutrition from Eastern Michigan University and a Ph.D. in Biomedical Informatics, Nanomedicine and Clinical Informatics from Rutgers University. Dr. Pastore has spent over a decade practicing "applied biochemistry" as he treats some of the world’s greatest athletes from the NHL, MLB, NFL, Olympics and endurance sports, as well CEOs and top executives of Fortune 500 companies.

On Migraines 01.11.2019, 23:32
On Migraines

<p class="p1">Dr. Pastore shares his history with migraines and the signs, symptoms, causes, treatments and science behind migraines.</p> <p class="p1">Talking points include:</p> <ul> <li class="p1">The 4 stages of the migraine, including the “migraine hangover”</li> <li class="p1">A sub-class of migraines called allodynia -<span class="Apple-converted-space"> </span> the experience of pain from stimuli that isn't normally painful (ex - pain caused by steam/water from a shower)</li> <li class="p1">What triggers migraines, including MSG, aspartame, and tyramine-containing foods such as dairy, yeast extract & fermented foods </li> <li class="p1">The prevalence of dairy being a trigger in Dr. Pastore’s migraine patients & how to follow a one-month dairy elimination diet</li> <li class="p1">Why it's probably NOT the weather causing your migraine </li> </ul> <p> </p>

On Nutritional Deficiencies and Increased Infection Risk for the Celiac Population 25.10.2019, 21:23
On Nutritional Deficiencies and Increased Infection Risk for the Celiac Population

<p class="p1">Dr. Pastore covers the typical nutritional deficiencies the newly diagnosed celiac patient may experience, the mistakes practitioners make when attempting to correct these deficiencies, and what YOU can do to be your own health-care advocate.</p> <p class="p2"> </p> <p class="p1">He then explains why those with celiac diseases (following a gluten-free diet or not), or even those with a gluten intolerance are more at risk to pneumococcal infections such as bronchitis, sinusitis, meningitis, and sepsis and what you can do to prevent this.</p> <p class="p2"> </p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog">https://drrobertpastore.com/blog</a></span></p> <p class="p2"> </p> <p class="p1"><strong>Blood test names:</strong></p> <p class="p1"><span class="s1">Vitamin D:</span> 25-hydroxy vitamin D</p> <p class="p2"> </p> <p class="p1"><span class="s1">Magnesium:</span> Magnesium, RBC</p> <p class="p2"> </p> <p class="p1"><span class="s1">Omega 3 fatty acids (EPA/DHA)</span>: EPA/DHA plasma & red blood cell membrane analysis</p> <p class="p2"> </p> <p class="p1"><span class="s1">Zinc:</span> Serum or plasma zinc concentration</p> <p class="p2"> </p> <p class="p1"><span class="s1">Iron:</span> Serum Iron & Transferrin & TIBC (total iron binding capacity)& UIBC (unsaturated iron-binding capacity) & Serum ferritin</p> <p class="p1"> </p> <p class="p1"> </p> <p class="p1"><span class="s1"><strong>Food sources for each vitamin/nutrient/mineral:</strong></span></p> <p class="p1"> </p> <p class="p3"><span class="s2"><strong>Iron:</strong> <a rel="nofollow" href= "https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/"><span class="s3"> https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class= "s2"><strong>Magnesium: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/"><span class="s3">https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class="s2"><strong>Zinc: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/"><span class="s3">https://ods.od.nih.gov/factsheets/Zinc-HealthProfessional/</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class= "s2"><strong>Choline: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/"><span class="s3">https://ods.od.nih.gov/factsheets/Choline-HealthProfessional/</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class="s2"><strong>Vitamin D: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/"><span class="s3">https://ods.od.nih.gov/factsheets/VitaminD-HealthProfessional/</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class="s2"><strong>Omega 3 EPA: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/pubs/usdandb/EPA-Content.pdf#search=%22omega%203%22"><span class="s3">https://ods.od.nih.gov/pubs/usdandb/EPA-Content.pdf#search=%22omega%203%22</span></a></span></p> <p class="p1"> </p> <p class="p3"><span class="s2"><strong>Omega 3 DHA: </strong><a rel="nofollow" href= "https://ods.od.nih.gov/pubs/usdandb/DHA-Content.pdf#search=%22omega%203%22"><span class="s3">https://ods.od.nih.gov/pubs/usdandb/DHA-Content.pdf#search=%22omega%203%22</span></a></span></p>

The Neurochemistry of Concussions 18.10.2019, 18:48
The Neurochemistry of Concussions

<p class="p1">(Part 2 of 2)</p> <p class="p1">Dr. Pastore and Lexie dive into what is happening to the brain chemically in the days, weeks and months after a concussion and why these neurological changes cause concussion symptoms including loss of consciousness, laps in memory, fatigue, anxiety, memory, food cravings and even catching a cold.</p> <p class="p1"> </p> <p class="p1">Links mentioned:</p> <p class="p3"><a rel="nofollow" href= "http://poweronpoweroff.com">poweronpoweroff.com</a></p>

On Concussions 12.10.2019, 01:09
On Concussions

<p class="p1">[Part 1 of 2]</p> <p class="p2"> </p> <p class="p1">Dr. Pastore and Lexie introduce concussions and traumatic brain injuries (TBI) - including what causes a concussion, the common symptoms, recovery time, and what to do to recover as quickly and efficiently as possible.</p> <p class="p2"> </p> <p class="p1">Stay tuned for a more in-depth look at “The Neurochemistry of Concussions” next episode.</p> <p class="p2"> </p> <p class="p1"><strong>Links mentioned:</strong></p> <p class="p3"> </p> <p class="p1">Light therapy tools:</p> <p class="p4"><span class="s1"><a rel="nofollow" href= "https://www.usa.philips.com/c-m-pe/light-therapy">https://www.usa.philips.com/c-m-pe/light-therapy</a></span></p> <p class="p2"> </p> <p class="p1">Physical exercise for concussion recovery:</p> <p class="p4"><span class="s1"><a rel="nofollow" href= "http://www.eldoamethod.com/about">http://www.eldoamethod.com/about</a></span></p>

On Infertility & Celiac Disease 27.09.2019, 21:28
On Infertility & Celiac Disease

<p class="p1">Infertility may be the one and only symptom that a woman OR man has undiagnosed celiac disease - there may be no gastrointestinal distress or typical “digestion” symptoms you’d assume to be present.a</p> <p class="p1">Dr. Pastore discusses the most recent study around celiac disease research and then dives into the studies around infertility in celiacs, and how for Dr. Pastore’s celiac patients, following a gluten-free diet led to a 100% success rate for a couple to be able to conceive.</p> <p class="p2"> </p> <p class="p1"><strong>Infertility & Celiac Disease:</strong></p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-28-could-your-infertility-be-a-symptom-of-celiac-disease"> https://drrobertpastore.com/blog/2019-08-28-could-your-infertility-be-a-symptom-of-celiac-disease</a></span></p> <p class="p2"> </p> <p class="p1"><strong>What to do if you think you have celiac disease:</strong></p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease/"> https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease/</a></span></p>

Celiac Disease: High Risk Groups, Related Disorders and Comorbidities 20.09.2019, 16:00
Celiac Disease: High Risk Groups, Related Disorders and Comorbidities

<p class="p1">Comorbidity is the presence of one or more additional medical conditions co-occurring with a primary condition.</p> <p class="p1">Dr. Pastore discusses the most common comorbidities (disorders and diseases) that are connected with celiac disease and the research that uncovers why this is the case. He also elaborates on the intestinal epithelial barrier, it’s importance for immunity and how gliadin (the protein found in gluten) reacts with zonulin to causes tight junction dysfunction in the small intestine.</p> <p class="p1"> </p> <p class="p1">-People with the diseases/disorders discussed may be at a higher risk of having celiac disease</p> <p class="p2"> </p> <p class="p1">-Celiac disease may be causing the signs/symptoms of other medical conditions and those may be reduced/eliminated once going gluten-free</p> <p class="p2"> </p> <p class="p1">-Those that know they have celiac disease should also be tested for the mentioned medical conditions, especially if there is a family history</p> <p class="p2"> </p> <p class="p2"> </p> <p class="p1"><strong>Articles mentioned:</strong></p> <p class="p2"> </p> <p class="p3"><em>Celiac Disease: High Risk Groups, Related Disorders and Comorbidities</em></p> <p class="p4"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-09-12-celiac-disease-high-risk-groups-related-disorders-and-comorbidities"> https://drrobertpastore.com/blog/2019-09-12-celiac-disease-high-risk-groups-related-disorders-and-comorbidities</a></span></p> <p class="p2"> </p> <p class="p3"><em>What do you do if you think you may have celiac disease</em></p> <p class="p4"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease"> https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease</a></span></p>

On Obesity & Celiac Disease 13.09.2019, 17:00
On Obesity & Celiac Disease

<p class="p1">Dr. Pastore discusses the topic of obesity and the newest emerging studies showing it as one of the most common symptoms of undiagnosed celiac disease.</p> <p class="p1">He explains the misconception that undiagnosed celiac patients would appear underweight due to malnutrition; as well as what is physiologically happening in the gastrointestinal tract and throughout the body for those that present obesity as a symptom.</p> <p class="p2"> </p> <p class="p1">Dr. Pastore’s articles mentioned in the podcast:</p> <p class="p2"> </p> <p class="p1"><strong>Celiac Disease: A Clinical Chameleon</strong></p> <p class="p1"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-19-celiac-disease-a-clinical-chameleon"> https://drrobertpastore.com/blog/2019-08-19-celiac-disease-a-clinical-chameleon</a></span></p> <p class="p4"> </p> <p class="p4"> </p> <p class="p1"><strong>What do you do if you think you may have celiac disease?</strong></p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease"> https://drrobertpastore.com/blog/2019-08-26-what-do-you-do-if-you-think-you-may-have-celiac-disease</a></span></p> <p class="p2"> </p> <p class="p2"> </p> <p class="p1"><strong>The Celiac and Obesity Connection</strong></p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://drrobertpastore.com/blog/2019-08-30-the-celiac-and-obesity-connection/"> https://drrobertpastore.com/blog/2019-08-30-the-celiac-and-obesity-connection/</a></span></p> <p class="p2"> </p> <p class="p2"> </p>

On Gene Variances 06.09.2019, 16:00
On Gene Variances

<p class="p1">Dr. Pastore and Lexie cover how certain variations of specific genes can affect your performance, your nutrition, your cravings and even how food tastes.</p> <p class="p1"> </p> <p class="p1"><strong>In-depth topics include how genetics affect:</strong></p> <ul> <li class="p1">High carbohydrate consumption and low HDL cholesterol levels</li> <li class="p1">How food tastes, and why some people can never get enough sugar</li> <li class="p1">How your risk for tendon/ligament/joint injury is increased/decreased</li> <li class="p1">Over-eating and difficulty losing weight</li> </ul> <p class="p2"> </p> <p class="p2"> </p> <p class="p2"> </p> <p class="p1"><span class="s1"><strong>Genetic SNPs covered in the episode:</strong></span></p> <p class="p2"> </p> <p class="p1"><strong>KCTD10-GG</strong></p> <p class="p1"><strong>MMAB-GG</strong></p> <p class="p1"><strong>MVK</strong></p> <p class="p1"><em>May cause low HDL (“good”) cholesterol levels with high carbohydrate consumption (~231g+ per day)</em></p> <p class="p2"> </p> <p class="p1"><strong>SLC2A2 rs5400 - T allele (even just one)</strong></p> <p class="p1"><em>“Sweet tooth” gene, linked to over-eating, not feeling satisfied after sugar consumption, less sensitive to feeling the affects of high glucose levels in blood</em></p> <p class="p2"> </p> <p class="p1"><strong>TAS1R3-AA</strong></p> <p class="p1"><strong>TAS1R3-GA</strong></p> <p class="p1"><em>Sugar tastes less sweet, increases the likelihood over overconsumption of sugar and artificial sweeteners</em></p> <p class="p2"> </p> <p class="p1"><strong>TAS2R38-C allele</strong></p> <p class="p1"><strong>TAS2R38-G allele</strong></p> <p class="p1"><em>Do not like the taste of bitter foods (coffee, broccoli, kale, Brussels sprouts), over-salt or sweeten foods to cover up the taste</em></p> <p class="p2"> </p> <p class="p1"><strong>TAS2R38-TT</strong></p> <p class="p1"><em>Find bitter foods less bitter than other people (enjoy broccoli, cabbage, kale, etc)</em></p> <p class="p2"> </p> <p class="p1"><strong>COL5A1-TT</strong></p> <p class="p1"><em>Decreased elasticity and range of motion in joints. Increased risk of injuring joints, connective tissue (tendons/ligaments) and soft tissue.</em></p> <p class="p2"> </p> <p class="p1"><strong>COL5A1-CC</strong></p> <p class="p1"><em>Protective genotype, reduced rate of tendon injury</em></p> <p class="p2"> </p> <p class="p1"><strong>COL1A1-TT</strong></p> <p class="p1"><em>Decreased risk of injuring joints, connective tissue (tendons/ligaments) and soft tissue.</em></p> <p class="p2"> </p> <p class="p1"><strong>GDF5-T allele</strong></p> <p class="p1"><em>Increased risk for joint injuries, can be a warning sign of early (mid-40’s) onset osteoarthritis</em></p> <p class="p2"> </p> <p class="p1"><strong>MC4R-C allele</strong></p> <p class="p1"><strong>KCDT15-C allele</strong></p> <p class="p1"><em>Increases likelihood of higher BMI (from fat mass), slows the process of weight loss, can cause more cravings for higher caloric/processed food intake</em></p> <p class="p2"> </p> <p class="p1"><strong>COMT-GG</strong></p> <p class="p1"><em>Increases the likelihood to overeat</em></p> <p class="p2"> </p> <p class="p1"><strong>SHTB2, LEP, PCSK1-2,</strong> and <strong>FTO</strong> are currently being researched for their connection to obesity.</p>

On Alzheimer’s Disease - a New Type of Diabetes 30.08.2019, 23:49
On Alzheimer’s Disease - a New Type of Diabetes

<p class="p1">Dr. Pastore and Lexie review diabetes, Alzheimer’s disease, why the emerging scientific evidence is showing that Alzheimer’s disease may be Type 3 diabetes, and what you can do NOW to decrease the likelihood of developing these diseases. </p> <p class="p2"> </p> <p class="p1"><strong>Some important facts:</strong></p> <p class="p1">Prolonged elevated glucose (blood sugar) levels damage blood vessels in the brain, disrupt neurotransmitters, and cause brain cell inflammation and neuronal cell death.</p> <p class="p2"> </p> <p class="p1">Type 2 diabetes increases the likelihood of developing Alzheimer’s later in life.</p> <p class="p2"> </p> <p class="p1">30% of the population carries the <strong>APO-E4 gene</strong>, those with 2 copies - increase the likelihood of those individuals developing cardiovascular disease, type 2 diabetes and Alzheimer’s.</p> <p class="p2"> </p> <p class="p1">Online Order for Genetic Testing:</p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://www.23andme.com/dna-health-ancestry/">https://www.23andme.com/dna-health-ancestry/</a></span></p> <p class="p2"> </p> <p class="p1">Triglyceride and Glucose Index to determine Insulin Resistance:</p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://www.mdapp.co/tyg-index-calculator-359/">https://www.mdapp.co/tyg-index-calculator-359/</a></span></p> <p class="p2"> </p> <p class="p1">BMI Calculator:</p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm"> https://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm</a></span></p> <p class="p2"> </p> <p class="p1">For fish/seafood mercury levels, click “Show Full Table” here:</p> <p class="p3"><span class="s1"><a rel="nofollow" href= "https://www.ewg.org/research/ewgs-good-seafood-guide/executive-summary"> https://www.ewg.org/research/ewgs-good-seafood-guide/executive-summary</a></span></p>

On New Food Technologies 23.08.2019, 16:00
On New Food Technologies

<p class="p1">Dr. Pastore and Lexie discuss emerging foods in society today, including:</p> <p class="p2"> </p> <p class="p1">-The artificial sweetener <strong>allulose</strong>, how it’s made and why you should be mindful of dosages</p> <p class="p2"> </p> <p class="p1">-Plant-based “meats” such as the <strong>Impossible Burger & Beyond Meat</strong>, their protein quality and the downsides to how they are made & processed</p> <p class="p2"> </p> <p class="p1">-An up & coming plant-based protein source high in nutrients with a full amino acid profile known as <strong>duckweed</strong></p>